Eva Sapi, Ph.D.


1995 Eotvos Lorand University 

Budapest, Hungary 
Ph.D. Genetics and Molecular Biology 
1987 Eotvos Lorand University 

Budapest, Hungary 
M.S. Genetics and Molecular Biology 


Eva Sapi Ph.D. is a Professor, Department Chair and University Research Scholar at the Department of Biology and Environmental Science where she teaches undergraduate and graduate biology courses and carries out Lyme disease research with her graduate students.

Her research interest is to investigate the different forms of Borrelia burgdorferi for the better understanding how Borrelia can hide from the immune system as well as from antimicrobial therapies. Her recent research shows that Borrelia burgdorferi is capable forming a protective layer around itself ? called biofilm ? which could render it to be very resistant to antibiotics and provide a logical explanation as to why extensive antibiotic treatment for patients with a tick-bite history could fail. The goal of her research group is to fully characterize this novel form and to identify novel antibacterial agents that are effective in killing all forms of Borrelia burgdorferi. 

Dr. Sapi organized and chaired six Lyme Disease Symposiums at the University of New Haven during the last several years. 

Find out more about Dr. Sapi and connect with her online: 

Lyme Disease Research Group  


Fields of Research

Lyme Disease, Pathogenic Biofilm, Antibiotics Resistance, Different Morphology of Borrelia burgdorferi

Recent Articles

Middelveen MJ, Divya Burugu D, Akhila Poruri A, Jennie Burke J, Peter J Mayne PJ, Sapi E, Douglas G Kahn DG, Stricker RB. Association of spirochetal infection with Morgellons disease. [v1; ref status: indexed,] F1000Research 2013, 2:25 (doi: 10.3410/f1000research.2-25.v1). 

Sapi E, Pabbati N, Datar D, Davies EM, Rattalle A, Kuo BA. Culture Conditions For The Growth and Detection of Borrelia from Human Serum. International Journal of Medical Sciences 2013 10(4):362-376. doi:10.7150/ijms.5698. 

Sapi E, Bastian SL, Mpoy CM, Scott S, Rattelle A, Pabbati N, Poruri A, Burugu D, Theophilus PAS, Pham TV, Datar D, Dhaliwal NK, MacDonald A, Rossi MJ, Sinha SK and Luecke DF. Characterization of biofilm formation by Borrelia burgdorferi in vitro. PLoS ONE 2012 October 7(10): e48277. 

Sapi E, Kaur N, Anyanwu S, Luecke DF, Datar, A, Patel S, Rossi M, and Stricker RB. Evaluation of in vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi. Infection and Drug Resistance, 2011, 4(1) 97-113, 2011. 

Sapi E, Kaur N, Anyanwu S, Luecke DF, Datar, A, Patel S,  Rossi M, and Stricker RB. Evaluation of in vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi. Infection and Drug Resistance, 2011, 4(1) 97-113.

Datar, A., Kaur, N., Patel, S., Luecke D.F., and Sapi E. In vitro effectiveness of Samento and Banderol herbal extracts on the different morphological forms of Borrelia burgdorferi.Townsend Letter, 2010 July, 324, 87- 90.

Sapi, E: Biofilms: A New Hideout for Borrelia burgdorferi? Lyme Times 2009 February p45.

Sapi, E: Novel cancer stem therapy on the horizon. Cancer Biology & Therapy, 2009   8:18, 1-2.

Sapi, E. and MacDonald A. Biofilms of Borrelia burgdoferi in chronic cutaneous borreliosis. 2008 Am J Clin Pathol 129. p.988-989.